In a large skillet over medium-high heat, add the ground beef and crumble it with a spatula. Cook for 3 to 5 minutes.

Add in the diced onions and bell peppers, and continue cooking for another 4 to 5 minutes, or until the ground beef is nicely browned and no pink remains. Break the meat apart and stir as it cooks. During the last minute, stir in the minced garlic. Drain any excess grease, if needed.

Add the brown sugar (breaking it up if needed), garlic powder, and onion powder and stir to combine.

Pour in the tomato sauce, ketchup, yellow mustard, and Worcestershire sauce. Stir everything together and let it simmer for at least 10 minutes, stirring occasionally, until everything is heated through and the flavors meld.

Serve warm on toasted or plain hamburger buns or rolls with a side of sliced pickles.