Place Rub ingredients in a bowl and mix to combine.
Rub all over brisket with your hands.
Pour BBQ Sauce ingredients in the slow cooker. Mix then add the brisket and press brisket into sauce.
Cook on low for 8 to 10 hours, high for 4 to 5 hours.
Remove brisket from slow cooker onto a baking tray. Drizzle a few tablespoons of pan drippings on the brisket.
Pour liquid from slow cooker into a sauce pan and simmer over medium high heat until it thickens to a sauce like consistency.
Oven Method: Meanwhile, cook Brisket in 400 degree oven for 5 to 10 minutes until it begins to brown a bit. Remove from oven and mop on BBQ sauce cook for 5 minutes turn over and repeat for 5 to 10 minutes or until caramelized. Or do this on the BBQ Grill on medium high heat. Cook time for caramelization may be shorter. Then remove.
Slice Brisket thinly across the grain and serve with BBQ Sauce.